Is valacyclovir effective in the treatment of chickenpox (varicella)?

Updated: Aug 31, 2020
  • Author: Anthony J Papadopoulos, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Valacyclovir, the L-valyl ester of acyclovir, is a prodrug that has higher oral bioavailability than acyclovir. Valacyclovir is used in the treatment of herpes zoster, but no large-based clinical trials yet have demonstrated its efficacy in primary varicella infection of healthy, immunocompetent individuals.


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