When should oral acyclovir be used in the treatment of chickenpox (varicella) in adolescents?

Updated: Aug 31, 2020
  • Author: Anthony J Papadopoulos, MD; Chief Editor: Dirk M Elston, MD  more...
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Oral acyclovir should be considered for healthy persons at increased risk of severe varicella infections, most notably patients older than 12 years. Oral acyclovir therapy in this population (800 mg 5 times/d for 7 d), begun within 24 hours of onset of symptoms, has been shown to decrease the duration of lesions and pyrexia, while reducing other symptoms and disease duration.

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