When is varicella-zoster immune globulin (VariZIG) indicated?

Updated: Aug 31, 2020
  • Author: Anthony J Papadopoulos, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Varicella-zoster immune globulin (VariZIG) is indicated for use in highly susceptible, VZV-exposed immunocompromised or immunosuppressed populations. A live attenuated varicella vaccine (Oka strain) was approved by the FDA in 1995 for prophylactic use in healthy children and adults. [22, 23, 24, 25, 26]

While the current standard of care is with the antiviral agents discussed below, Lysimachia mauritiana extract appears promising as a potential agent. [27]

Also see the Guidelines section.


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