What are the possible clinical variants of chickenpox (varicella)?

Updated: Aug 31, 2020
  • Author: Anthony J Papadopoulos, MD; Chief Editor: Dirk M Elston, MD  more...
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Clinical variants of chickenpox infection also occur. Hemorrhagic lesions are rare and are most commonly associated with patients who are immunocompromised or immunosuppressed.

Bullous chickenpox is a rare variant in which bullae appear instead of the characteristic vesicles. [16, 17] The possibility of bullous impetigo from Staphylococcus aureus must be addressed, especially in a child with persistent fever or relapse after he or she appeared to be improving.

Bullous chickenpox may affect both children and adults and must be differentiated from other bullous disorders (eg, bullous pemphigoid, pemphigus). The course of the disease is believed to be unchanged, although a delay in diagnosis and treatment of elderly patients and immunocompromised patients may lead to serious morbidity.

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