Which medications in the drug class Antihistamines are used in the treatment of Chickenpox?

Updated: Aug 31, 2020
  • Author: Anthony J Papadopoulos, MD; Chief Editor: Dirk M Elston, MD  more...
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The symptoms of chickenpox such as pruritus in the pediatric population can be treated with oral antihistamines. Examples of antihistamines are diphenhydramine (Benadryl) and loratadine (Claritin, Alavert).

Diphenhydramine (Benadryl)

Diphenhydramine is a first-generation antihistamine with anticholinergic effects that binds to H1 receptors in the CNS and the body. It is often used for symptomatic relief of pruritus caused by the release of histamine in inflammatory reactions. Diphenhydramine may cause drowsiness.

Loratadine (Claritin, Alavert)

Loratadine selectively inhibits peripheral histamine H1-receptors. It provides relief of pruritus and has a decreased incidence of sedation compared with first-generation antihistamines.

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