Which medications in the drug class Immune globulins are used in the treatment of Chickenpox?

Updated: Aug 31, 2020
  • Author: Anthony J Papadopoulos, MD; Chief Editor: Dirk M Elston, MD  more...
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Immune globulins

For passive immunization, use varicella-zoster immune globulin, human (VariZIG), a human immunoglobulin preparation. This agent is indicated for use in highly susceptible, VZV-exposed immunocompromised or immunosuppressed populations.

Varicella zoster immune globulin, human (VariZIG)

When given within 10 days (ideally within 96 hours) of exposure, this agent modifies the course of disease but does not prevent it. Maximal effectiveness is seen with administration as soon as possible after exposure. It provides passive immunization to exposed individuals at high risk of complications from varicella. High-risk groups include immunocompromised children and adults, newborns of mothers with varicella shortly before or after delivery, premature infants, infants younger than 1 year, adults without evidence of immunity, and pregnant women. Administer by deep intramuscular injection in the deltoid muscle or in another large muscle mass. For neonates or infants, administer intramuscularly in anterolateral aspect of the thigh.

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