Which histologic findings are characteristic of lichen striatus?

Updated: Mar 26, 2020
  • Author: June Kim, MD; Chief Editor: Dirk M Elston, MD  more...
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The histopathologic results vary depending on the stage of evolution. Often, a polymorphic epidermal reaction pattern with variable spongiotic and lichenoid changes is seen in lichen striatus. However, unlike lichen planus, lichen striatus may result in a dense, usually perivascular, lymphohistiocytic infiltrate that extends deep into the dermis and that surrounds the hair follicles and eccrine sweat glands and ducts. Lymphoid infiltrates in the eccrine coil may mimic lupus or syringotropic mycosis fungoides, and the dense interface dermatitis may mimic conventional mycosis fungoides. [38, 39]  Granulomatous inflammation may also be present.

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