Which medications in the drug class Pyrimidine antagonists, topical are used in the treatment of Onycholysis?

Updated: Nov 20, 2020
  • Author: Melanie S Hecker, MD, MBA; Chief Editor: William D James, MD  more...
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Answer

Pyrimidine antagonists, topical

Topical pyrimidine antagonists inhibit cell growth and proliferation. Their mechanism is unknown for treating onycholysis. They are reported to be effective in the treatment of nail pitting and onycholysis associated with psoriasis.

Fluorouracil topical (Fluoroplex)

Fluorouracil is a fluorinated pyrimidine analog used in topical form to treat actinic keratoses. It has an unknown mechanism in treating onycholysis. Use 1% solution.


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