Which histological findings are characteristic of onycholysis?

Updated: Nov 20, 2020
  • Author: Melanie S Hecker, MD, MBA; Chief Editor: William D James, MD  more...
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Answer

Onycholysis is a clinical diagnosis and has no specific histology; however, if onychomycosis is the etiology for the onycholysis, hyphae are seen lying between the laminae of nail parallel to the surface. The ventral nail and the stratum corneum of the nail bed are affected preferentially. The epidermis may show spongiosis and focal parakeratosis. The inflammatory response in the dermis is minimal. Hyphae may be seen best using PAS stain.


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