What is the role of medications in the treatment of pseudofolliculitis barbae (PFB)?

Updated: Feb 07, 2019
  • Author: Thomas G Greidanus, MD; Chief Editor: Dirk M Elston, MD  more...
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Hydrocortisone cream is effective in reducing inflammation. Topical and oral antibiotics are used when secondary infection is evident. Tretinoin has shown promise in early pseudofolliculitis barbae. Chemical depilatories are preferential to shaving for some patients.

Chemical depilatories are effective alternatives to shaving for some patients. They work by breaking disulfide bonds in hair follicles. Barium sulfide is a fast-acting depilatory powder that is mixed with water to form a paste. Similarly, calcium thioglycolate is an effective depilatory that is left on for 10-15 minutes for effective hair removal.

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