Which medications in the drug class Antineoplastics, Antimetabolite are used in the treatment of Porokeratosis?

Updated: Oct 09, 2020
  • Author: Amarateedha Prak LeCourt, MD; Chief Editor: William D James, MD  more...
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Answer

Antineoplastics, Antimetabolite

These agents inhibit cell growth and proliferation.

Fluorouracil topical (Efudex, Carac, Fluoroplex)

Fluorouracil is preferentially taken up by cells that are dividing abnormally and rapidly; it interferes with DNA and RNA synthesis and leads to death of the abnormal cells. Fluorouracil 5% cream is most commonly used.; 1% cream may be used in thin-skinned areas.


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