Which medications in the drug class Calcineurin Inhibitors are used in the treatment of Porokeratosis?

Updated: Oct 09, 2020
  • Author: Amarateedha Prak LeCourt, MD; Chief Editor: William D James, MD  more...
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Calcineurin Inhibitors

These agents suppress the immune system by preventing interleukin-2 production in T cells.

Tacrolimus ointment (Protopic)

Tacrolimus is hypothesized to amplify the innate immune response in keratinocytes and prevent the proliferation of the abnormal keratinocytes, thus leading to the improvement in lesions. However, further research and controlled studies with a larger patient population and long-term follow up are needed to evaluate its true effectiveness.

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