What is the prevalence of acquired angioedema (AAE) due to C1 inhibitor (C1-INH) deficiency (C1-INH-AAE)?

Updated: May 20, 2020
  • Author: Amanda T Moon, MD; Chief Editor: William D James, MD  more...
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Answer

Acquired angioedema is rare. Only approximately 150 cases have been reported in the medical literature worldwide.

Racial and sexual differences in incidence

Persons of any race can be affected by acquired angioedema. Men and women are equally affected.

Age-related differences in incidence

The onset of acquired angioedema is most common after the fourth decade of life, whereas the usual onset of hereditary acquired angioedema (HAE) is in the second decade.


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