What is the role of brain imaging in the workup of vasculitis?

Updated: Dec 10, 2018
  • Author: Nadia Jennifer Chiara Luca, MD; Chief Editor: Lawrence K Jung, MD  more...
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Answer

These studies may reveal acute ischemia or hemorrhage in patients with CNS symptoms

In large or medium-vessel childhood PACNS, T2-hyperintense focal areas of acute ischemia in a vascular distribution is noted. Diffusion weighted imaging (DWI) findings are positive. Vessel wall enhances with gadolinium.

In small-vessel childhood PACNS, T2-fluid-attenuated inversion-recovery (FLAIR) hyperintensities that do not conform to a vascular territory are noted. DWI findings are negative.


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