Which conditions that cause elevated levels of sweat chloride should be included in the differential diagnoses of cystic fibrosis (CF)?

Updated: Sep 28, 2020
  • Author: Girish D Sharma, MD, FCCP, FAAP; Chief Editor: Kenan Haver, MD  more...
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Other causes of elevated levels of sweat chloride include the following:

  • Untreated adrenal insufficiency

  • Glycogen storage disease

  • Type I fucosidosis

  • Hypothyroidism

  • Vasopressin-resistant diabetes insipidus

  • Ectodermal dysplasia

  • Malnutrition

  • Mucopolysaccharidosis

  • Panhypopituitarism

  • Familial cholestasis

  • Familial hypoparathyroidism

  • Atopic dermatitis

  • Iatrogenic causes (ie, infusion of prostaglandin E1, improper technique)

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