What is the role of the lipids in the pathogenesis of asthma?

Updated: Jan 08, 2019
  • Author: Girish D Sharma, MD, FCCP, FAAP; Chief Editor: Kenan Haver, MD  more...
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Answer

A study that examined whether the lipid profile is associated with concurrent asthma concluded that the blood lipid profile is associated with asthma, airway obstruction, bronchial responsiveness, and aeroallergen sensitization in 7-year-old children. Caution must be applied before saying that asthma might be a systemic disorder. First, we don't know if the children with the elevated LDL  levels were more likely exposed to higher doses of inhaled, or systemic corticosteroids. The authors did find that those with worse lung function had higher LDL levels. However, it could also be that those children exercised less, a potential cause of obesity and abnormal lipid levels. The BMI was also not reported. [17, 18]


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